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A quantitative genome-wide RNAi screen in C. elegans for antifungal innate immunity genes

BACKGROUND: Caenorhabditis elegans has emerged over the last decade as a useful model for the study of innate immunity. Its infection with the pathogenic fungus Drechmeria coniospora leads to the rapid up-regulation in the epidermis of genes encoding antimicrobial peptides. The molecular basis of an...

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Detalles Bibliográficos
Autores principales: Zugasti, Olivier, Thakur, Nishant, Belougne, Jérôme, Squiban, Barbara, Kurz, C. Léopold, Soulé, Julien, Omi, Shizue, Tichit, Laurent, Pujol, Nathalie, Ewbank, Jonathan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850687/
https://www.ncbi.nlm.nih.gov/pubmed/27129311
http://dx.doi.org/10.1186/s12915-016-0256-3