A monoclonal natural human IgM protects axons in the absence of remyelination

BACKGROUND: Whereas demyelination underlies early neurological symptoms in multiple sclerosis (MS), axonal damage is considered critical for permanent chronic deficits. Intracerebral infection of susceptible mouse strains with Theiler’s murine encephalomyelitis virus (TMEV) results in chronic induce...

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Detalles Bibliográficos
Autores principales: Wootla, Bharath, Denic, Aleksandar, Warrington, Arthur E., Rodriguez, Moses
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850699/
https://www.ncbi.nlm.nih.gov/pubmed/27126523
http://dx.doi.org/10.1186/s12974-016-0561-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850699/
https://www.ncbi.nlm.nih.gov/pubmed/27126523
http://dx.doi.org/10.1186/s12974-016-0561-3

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