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Lipopolysaccharide Disrupts Mitochondrial Physiology in Skeletal Muscle via Disparate Effects on Sphingolipid Metabolism
Lipopolysaccharides (LPS) are prevalent pathogenic molecules that are found within tissues and blood. Elevated circulating LPS is a feature of obesity and sepsis, both of which are associated with mitochondrial abnormalities that are key pathological features of LPS excess. However, the mechanism of...
Autores principales: | Hansen, Melissa E., Simmons, Kurtis J., Tippetts, Trevor S., Thatcher, Mikayla O., Saito, Rex R., Hubbard, Sheryl T., Trumbull, Annie M., Parker, Brian A., Taylor, Oliver J., Bikman, Benjamin T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851226/ https://www.ncbi.nlm.nih.gov/pubmed/26529656 http://dx.doi.org/10.1097/SHK.0000000000000468 |
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