Dynamic m(6)A mRNA methylation directs translational control of heat shock response

The most abundant mRNA post-transcriptional modification is N(6)-methyladenosine (m(6)A) that has broad roles in RNA biology(1-5). In mammalian cells, the asymmetric distribution of m(6)A along mRNAs leaves relatively less methylation in the 5′ untranslated region (5′UTR) compared to other regions(6...

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Detalles Bibliográficos
Autores principales: Zhou, Jun, Wan, Ji, Gao, Xiangwei, Zhang, Xingqian, Qian, Shu-Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851248/
https://www.ncbi.nlm.nih.gov/pubmed/26458103
http://dx.doi.org/10.1038/nature15377

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851248/
https://www.ncbi.nlm.nih.gov/pubmed/26458103
http://dx.doi.org/10.1038/nature15377

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