Coronary Artery-Bypass-Graft Surgery Increases the Plasma Concentration of Exosomes Carrying a Cargo of Cardiac MicroRNAs: An Example of Exosome Trafficking Out of the Human Heart with Potential for Cardiac Biomarker Discovery

INTRODUCTION: Exosome nanoparticles carry a composite cargo, including microRNAs (miRs). Cultured cardiovascular cells release miR-containing exosomes. The exosomal trafficking of miRNAs from the heart is largely unexplored. Working on clinical samples from coronary-artery by-pass graft (CABG) surge...

Descripción completa

Detalles Bibliográficos
Autores principales: Emanueli, Costanza, Shearn, Andrew I. U., Laftah, Abas, Fiorentino, Francesca, Reeves, Barnaby C., Beltrami, Cristina, Mumford, Andrew, Clayton, Aled, Gurney, Mark, Shantikumar, Saran, Angelini, Gianni D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851293/
https://www.ncbi.nlm.nih.gov/pubmed/27128471
http://dx.doi.org/10.1371/journal.pone.0154274

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851293/
https://www.ncbi.nlm.nih.gov/pubmed/27128471
http://dx.doi.org/10.1371/journal.pone.0154274

Ejemplares similares