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Probing the Sophisticated Synergistic Allosteric Regulation of Aromatic Amino Acid Biosynthesis in Mycobacterium tuberculosis Using ᴅ-Amino Acids

Chirality plays a major role in recognition and interaction of biologically important molecules. The enzyme 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase (DAH7PS) is the first enzyme of the shikimate pathway, which is responsible for the synthesis of aromatic amino acids in bacteria and plant...

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Detalles Bibliográficos
Autores principales: Reichau, Sebastian, Blackmore, Nicola J., Jiao, Wanting, Parker, Emily J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851294/
https://www.ncbi.nlm.nih.gov/pubmed/27128682
http://dx.doi.org/10.1371/journal.pone.0152723