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A Cohesin-Based Partitioning Mechanism Revealed upon Transcriptional Inactivation of Centromere

Transcriptional inactivation of the budding yeast centromere has been a widely used tool in studies of chromosome segregation and aneuploidy. In haploid cells when an essential chromosome contains a single conditionally inactivated centromere (GAL-CEN), cell growth rate is slowed and segregation fid...

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Detalles Bibliográficos
Autores principales: Tsabar, Michael, Haase, Julian, Harrison, Benjamin, Snider, Chloe E., Eldridge, Brittany, Kaminsky, Lila, Hine, Rebecca M., Haber, James E., Bloom, Kerry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851351/
https://www.ncbi.nlm.nih.gov/pubmed/27128635
http://dx.doi.org/10.1371/journal.pgen.1006021