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A Cohesin-Based Partitioning Mechanism Revealed upon Transcriptional Inactivation of Centromere
Transcriptional inactivation of the budding yeast centromere has been a widely used tool in studies of chromosome segregation and aneuploidy. In haploid cells when an essential chromosome contains a single conditionally inactivated centromere (GAL-CEN), cell growth rate is slowed and segregation fid...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851351/ https://www.ncbi.nlm.nih.gov/pubmed/27128635 http://dx.doi.org/10.1371/journal.pgen.1006021 |