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Dendrimers Target the Ischemic Lesion in Rodent and Primate Models of Nonarteritic Anterior Ischemic Optic Neuropathy

INTRODUCTION: Polyamidoamine dendrimer nanoparticles (~ 4 nanometers) are inert polymers that can be linked to biologically active compounds. These dendrimers selectively target and accumulate in inflammatory cells upon systemic administration. Dendrimer-linked compounds enable sustained release of...

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Detalles Bibliográficos
Autores principales: Guo, Yan, Johnson, Mary A., Mehrabian, Zara, Mishra, Manoj K., Kannan, Rangaramanujam, Miller, Neil R., Bernstein, Steven L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851377/
https://www.ncbi.nlm.nih.gov/pubmed/27128315
http://dx.doi.org/10.1371/journal.pone.0154437