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High Throughput Screening Identifies Novel Lead Compounds with Activity against Larval, Juvenile and Adult Schistosoma mansoni

An estimated 600 million people are affected by the helminth disease schistosomiasis caused by parasites of the genus Schistosoma. There is currently only one drug recommended for treating schistosomiasis, praziquantel (PZQ), which is effective against adult worms but not against the juvenile stage....

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Detalles Bibliográficos
Autores principales: Mansour, Nuha R., Paveley, Ross, Gardner, J. Mark F., Bell, Andrew S., Parkinson, Tanya, Bickle, Quentin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851381/
https://www.ncbi.nlm.nih.gov/pubmed/27128493
http://dx.doi.org/10.1371/journal.pntd.0004659