Cargando…
High Throughput Screening Identifies Novel Lead Compounds with Activity against Larval, Juvenile and Adult Schistosoma mansoni
An estimated 600 million people are affected by the helminth disease schistosomiasis caused by parasites of the genus Schistosoma. There is currently only one drug recommended for treating schistosomiasis, praziquantel (PZQ), which is effective against adult worms but not against the juvenile stage....
Autores principales: | Mansour, Nuha R., Paveley, Ross, Gardner, J. Mark F., Bell, Andrew S., Parkinson, Tanya, Bickle, Quentin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851381/ https://www.ncbi.nlm.nih.gov/pubmed/27128493 http://dx.doi.org/10.1371/journal.pntd.0004659 |
Ejemplares similares
-
The discovery of a novel series of compounds with single-dose efficacy against juvenile and adult Schistosoma species
por: Gardner, J. Mark F., et al.
Publicado: (2021) -
Comparison of Microscopy and Alamar Blue Reduction in a Larval Based Assay for Schistosome Drug Screening
por: Mansour, Nuha R., et al.
Publicado: (2010) -
Gene Expression Patterns in Larval Schistosoma mansoni Associated with Infection of the Mammalian Host
por: Parker-Manuel, Sophia J., et al.
Publicado: (2011) -
Functional genomic characterization of neoblast-like stem cells in larval Schistosoma mansoni
por: Wang, Bo, et al.
Publicado: (2013) -
Quantitative High-Throughput Screen Identifies Inhibitors of the Schistosoma mansoni Redox Cascade
por: Simeonov, Anton, et al.
Publicado: (2008)