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Quorum-Sensing Synchronization of Synthetic Toggle Switches: A Design Based on Monotone Dynamical Systems Theory

Synthetic constructs in biotechnology, biocomputing, and modern gene therapy interventions are often based on plasmids or transfected circuits which implement some form of “on-off” switch. For example, the expression of a protein used for therapeutic purposes might be triggered by the recognition of...

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Detalles Bibliográficos
Autores principales: Nikolaev, Evgeni V., Sontag, Eduardo D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851387/
https://www.ncbi.nlm.nih.gov/pubmed/27128344
http://dx.doi.org/10.1371/journal.pcbi.1004881