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Validation of N-myristoyltransferase as Potential Chemotherapeutic Target in Mammal-Dwelling Stages of Trypanosoma cruzi

BACKGROUND: Trypanosoma cruzi causes Chagas disease, an endemic and debilitating illness in Latin America. Lately, owing to extensive population movements, this neglected tropical disease has become a global health concern. The two clinically available drugs for the chemotherapy of Chagas disease ha...

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Detalles Bibliográficos
Autores principales: Herrera, Linda J., Brand, Stephen, Santos, Andres, Nohara, Lilian L., Harrison, Justin, Norcross, Neil R., Thompson, Stephen, Smith, Victoria, Lema, Carolina, Varela-Ramirez, Armando, Gilbert, Ian H., Almeida, Igor C., Maldonado, Rosa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851402/
https://www.ncbi.nlm.nih.gov/pubmed/27128971
http://dx.doi.org/10.1371/journal.pntd.0004540