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Validation of N-myristoyltransferase as Potential Chemotherapeutic Target in Mammal-Dwelling Stages of Trypanosoma cruzi
BACKGROUND: Trypanosoma cruzi causes Chagas disease, an endemic and debilitating illness in Latin America. Lately, owing to extensive population movements, this neglected tropical disease has become a global health concern. The two clinically available drugs for the chemotherapy of Chagas disease ha...
Autores principales: | Herrera, Linda J., Brand, Stephen, Santos, Andres, Nohara, Lilian L., Harrison, Justin, Norcross, Neil R., Thompson, Stephen, Smith, Victoria, Lema, Carolina, Varela-Ramirez, Armando, Gilbert, Ian H., Almeida, Igor C., Maldonado, Rosa A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851402/ https://www.ncbi.nlm.nih.gov/pubmed/27128971 http://dx.doi.org/10.1371/journal.pntd.0004540 |
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