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Controlling Arteriogenesis and Mast Cells Are Central to Bioengineering Solutions for Critical Bone Defect Repair Using Allografts

Although most fractures heal, critical defects in bone fail due to aberrant differentiation of mesenchymal stem cells towards fibrosis rather than osteogenesis. While conventional bioengineering solutions to this problem have focused on enhancing angiogenesis, which is required for bone formation, r...

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Detalles Bibliográficos
Autores principales: Antebi, Ben, Zhang, Longze, Sheyn, Dmitriy, Pelled, Gadi, Zhang, Xinping, Gazit, Zulma, Schwarz, Edward M., Gazit, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851447/
https://www.ncbi.nlm.nih.gov/pubmed/27141513
http://dx.doi.org/10.3390/bioengineering3010006