Expression of CD39 on Activated T Cells Impairs their Survival in Older Individuals

In an immune response, CD4(+) T cells expand into effector T cells and then contract to survive as long-lived memory cells. To identify age-associated defects in memory cell formation, we profiled activated CD4(+) T cells and found an increased induction of the ATPase CD39 with age. CD39(+) CD4(+) T...

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Detalles Bibliográficos
Autores principales: Fang, Fengqin, Yu, Mingcan, Cavanagh, Mary M., Saunders, Jessica Hutter, Qi, Qian, Ye, Zhongde, Le Saux, Sabine, Sultan, William, Turgano, Emerson, Dekker, Cornelia L., Tian, Lu, Weyand, Cornelia M., Goronzy, Jörg J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851554/
https://www.ncbi.nlm.nih.gov/pubmed/26832412
http://dx.doi.org/10.1016/j.celrep.2016.01.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851554/
https://www.ncbi.nlm.nih.gov/pubmed/26832412
http://dx.doi.org/10.1016/j.celrep.2016.01.002

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