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Higher levels of TIMP-1 expression are associated with a poor prognosis in triple-negative breast cancer

BACKGROUND: Tissue inhibitor of metalloproteinases-1 (TIMP-1) is a multifunctional protein that can directly regulate apoptosis and metastasis. In this study, we investigated the functional and molecular mechanisms by which TIMP-1 influences triple-negative breast cancer (TNBC). METHODS: The express...

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Detalles Bibliográficos
Autores principales: Cheng, Guangcun, Fan, Xuemei, Hao, Mingang, Wang, Jinglong, Zhou, Xiaoming, Sun, Xueqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851824/
https://www.ncbi.nlm.nih.gov/pubmed/27130446
http://dx.doi.org/10.1186/s12943-016-0515-5