ACTH Prevents Deficits in Fear Extinction Associated with Early Life Seizures

OBJECTIVE: Early life seizures (ELS) are often associated with cognitive and psychiatric comorbidities that are detrimental to quality of life. In a rat model of ELS, we explored long-term cognitive outcomes in adult rats. Using ACTH, an endogeneous HPA-axis hormone given to children with severe epi...

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Detalles Bibliográficos
Autores principales: Massey, Andrew T., Lerner, David K., Holmes, Gregory L., Scott, Rod C., Hernan, Amanda E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852169/
https://www.ncbi.nlm.nih.gov/pubmed/27199888
http://dx.doi.org/10.3389/fneur.2016.00065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852169/
https://www.ncbi.nlm.nih.gov/pubmed/27199888
http://dx.doi.org/10.3389/fneur.2016.00065

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