Cargando…
ACTH Prevents Deficits in Fear Extinction Associated with Early Life Seizures
OBJECTIVE: Early life seizures (ELS) are often associated with cognitive and psychiatric comorbidities that are detrimental to quality of life. In a rat model of ELS, we explored long-term cognitive outcomes in adult rats. Using ACTH, an endogeneous HPA-axis hormone given to children with severe epi...
Autores principales: | Massey, Andrew T., Lerner, David K., Holmes, Gregory L., Scott, Rod C., Hernan, Amanda E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852169/ https://www.ncbi.nlm.nih.gov/pubmed/27199888 http://dx.doi.org/10.3389/fneur.2016.00065 |
Ejemplares similares
-
Attention Deficit Associated with Early Life Interictal Spikes in a Rat Model Is Improved with ACTH
por: Hernan, Amanda E., et al.
Publicado: (2014) -
Impact of Life History on Fear Memory and Extinction
por: Remmes, Jasmin, et al.
Publicado: (2016) -
Dopamine in Fear Extinction
por: Salinas-Hernández, Ximena I., et al.
Publicado: (2021) -
Gradual extinction prevents the return of fear: implications for the discovery of state
por: Gershman, Samuel J., et al.
Publicado: (2013) -
Unrelenting Fear Under Stress: Neural Circuits and Mechanisms for the Immediate Extinction Deficit
por: Maren, Stephen
Publicado: (2022)