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Increased ZAP70 Is Involved in Dry Skin Pruritus in Aged Mice

Dry skin pruritus is common in the elderly. Recent reports show that T-cell signal path is involved in dry skin pruritus. Zeta-chain-associated protein kinase 70 (ZAP70), as a T-cell receptor, may induce interleukin 2 (IL-2) secretion and promote nerve growth factor (NGF) secretion in skin. This stu...

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Detalles Bibliográficos
Autores principales: Zhao, Nan, Gu, Min, Yang, Wenxiu, Zhang, Man, Tian, Qi, Ru, Liyan, Lü, Yang, Yu, Weihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852331/
https://www.ncbi.nlm.nih.gov/pubmed/27195291
http://dx.doi.org/10.1155/2016/6029538