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Age-dependent development of liver fibrosis in Glmp(gt/gt) mice
BACKGROUND: Mice lacking glycosylated lysosomal membrane protein (Glmp(gt/gt) mice) have liver fibrosis as the predominant phenotype due to chronic liver injury. The Glmp(gt/gt) mice grow and reproduce at the same rate as their wild-type siblings. Life expectancy is around 18 months. METHODS: Wild-t...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852418/ https://www.ncbi.nlm.nih.gov/pubmed/27141234 http://dx.doi.org/10.1186/s13069-016-0042-4 |