Cargando…

Age-dependent development of liver fibrosis in Glmp(gt/gt) mice

BACKGROUND: Mice lacking glycosylated lysosomal membrane protein (Glmp(gt/gt) mice) have liver fibrosis as the predominant phenotype due to chronic liver injury. The Glmp(gt/gt) mice grow and reproduce at the same rate as their wild-type siblings. Life expectancy is around 18 months. METHODS: Wild-t...

Descripción completa

Detalles Bibliográficos
Autores principales: Nesset, Cecilie K., Kong, Xiang Yi, Damme, Markus, Schjalm, Camilla, Roos, Norbert, Løberg, Else Marit, Eskild, Winnie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852418/
https://www.ncbi.nlm.nih.gov/pubmed/27141234
http://dx.doi.org/10.1186/s13069-016-0042-4