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ESCRT-II controls retinal axon growth by regulating DCC receptor levels and local protein synthesis

Endocytosis and local protein synthesis (LPS) act coordinately to mediate the chemotropic responses of axons, but the link between these two processes is poorly understood. The endosomal sorting complex required for transport (ESCRT) is a key regulator of cargo sorting in the endocytic pathway, and...

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Detalles Bibliográficos
Autores principales: Konopacki, Filip A., Wong, Hovy Ho-Wai, Dwivedy, Asha, Bellon, Anaïs, Blower, Michael D., Holt, Christine E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852451/
https://www.ncbi.nlm.nih.gov/pubmed/27248654
http://dx.doi.org/10.1098/rsob.150218