EZH2 regulates neuroepithelium structure and neuroblast proliferation by repressing p21

The function of EZH2 as a transcription repressor is well characterized. However, its role during vertebrate development is still poorly understood, particularly in neurogenesis. Here, we uncover the role of EZH2 in controlling the integrity of the neural tube and allowing proper progenitor prolifer...

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Detalles Bibliográficos
Autores principales: Akizu, Naiara, García, María Alejandra, Estarás, Conchi, Fueyo, Raquel, Badosa, Carmen, de la Cruz, Xavier, Martínez-Balbás, Marian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852452/
https://www.ncbi.nlm.nih.gov/pubmed/27248655
http://dx.doi.org/10.1098/rsob.150227

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852452/
https://www.ncbi.nlm.nih.gov/pubmed/27248655
http://dx.doi.org/10.1098/rsob.150227

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