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Constitutive translation of human α-synuclein is mediated by the 5′-untranslated region
Genetic and biochemical studies have established a central role for α-synuclein (SNCA) accumulation in the pathogenesis of Parkinson's disease. Uncovering and subsequently interfering with physiological mechanisms that control SNCA expression is one approach to limit disease progression. To thi...
Autores principales: | Koukouraki, Pelagia, Doxakis, Epaminondas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852460/ https://www.ncbi.nlm.nih.gov/pubmed/27248657 http://dx.doi.org/10.1098/rsob.160022 |
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