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A closed conformation of the Caenorhabditis elegans separase–securin complex

The protease separase plays a key role in sister chromatid disjunction and centriole disengagement. To maintain genomic stability, separase activity is strictly regulated by binding of an inhibitory protein, securin. Despite its central role in cell division, the separase and securin complex is poor...

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Detalles Bibliográficos
Autores principales: Bachmann, Gudrun, Richards, Mark W., Winter, Anja, Beuron, Fabienne, Morris, Edward, Bayliss, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852461/
https://www.ncbi.nlm.nih.gov/pubmed/27249343
http://dx.doi.org/10.1098/rsob.160032