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ChromNet: Learning the human chromatin network from all ENCODE ChIP-seq data

A cell’s epigenome arises from interactions among regulatory factors—transcription factors and histone modifications—co-localized at particular genomic regions. We developed a novel statistical method, ChromNet, to infer a network of these interactions, the chromatin network, by inferring conditiona...

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Detalles Bibliográficos
Autores principales: Lundberg, Scott M., Tu, William B., Raught, Brian, Penn, Linda Z., Hoffman, Michael M., Lee, Su-In
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852466/
https://www.ncbi.nlm.nih.gov/pubmed/27139377
http://dx.doi.org/10.1186/s13059-016-0925-0