Cargando…

Nucleolar activity and CENP-C regulate CENP-A and CAL1 availability for centromere assembly in meiosis

The centromere-specific histone CENP-A is the key epigenetic determinant of centromere identity. Whereas most histones are removed from mature sperm, CENP-A is retained to mark paternal centromeres. In Drosophila males we show that the centromere assembly factors CAL1 and CENP-C are required for mei...

Descripción completa

Detalles Bibliográficos
Autores principales: Kwenda, Lucretia, Collins, Caitriona M., Dattoli, Anna A., Dunleavy, Elaine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852514/
https://www.ncbi.nlm.nih.gov/pubmed/27095496
http://dx.doi.org/10.1242/dev.130625