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Structural basis for Mep2 ammonium transceptor activation by phosphorylation

Mep2 proteins are fungal transceptors that play an important role as ammonium sensors in fungal development. Mep2 activity is tightly regulated by phosphorylation, but how this is achieved at the molecular level is not clear. Here we report X-ray crystal structures of the Mep2 orthologues from Sacch...

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Detalles Bibliográficos
Autores principales: van den Berg, Bert, Chembath, Anupama, Jefferies, Damien, Basle, Arnaud, Khalid, Syma, Rutherford, Julian C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852598/
https://www.ncbi.nlm.nih.gov/pubmed/27088325
http://dx.doi.org/10.1038/ncomms11337