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Transmembrane protein TMEM170A is a newly discovered regulator of ER and nuclear envelope morphogenesis in human cells

The mechanism of endoplasmic reticulum (ER) morphogenesis is incompletely understood. ER tubules are shaped by the reticulons (RTNs) and DP1/Yop1p family members, but the mechanism of ER sheet formation is much less clear. Here, we characterize TMEM170A, a human transmembrane protein, which localize...

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Detalles Bibliográficos
Autores principales: Christodoulou, Andri, Santarella-Mellwig, Rachel, Santama, Niovi, Mattaj, Iain W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852765/
https://www.ncbi.nlm.nih.gov/pubmed/26906412
http://dx.doi.org/10.1242/jcs.175273