Red Cell Distribution Width and Mean Platelet Volume in Patients With Pityriasis Rosea
BACKGROUND: Pityriasis rosea (PR) is an inflammatory skin disorder of unknown etiology. However, it is suggested to be related with the reactivation of human herpes virus 7 (HHV-7) and/or HHV-6. It is sometimes diffucult to distinguish PR from PR-like drug eruptions and other inflammatory disorders,...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elmer Press
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852777/ https://www.ncbi.nlm.nih.gov/pubmed/27222672 http://dx.doi.org/10.14740/jocmr2535w |
_version_ | 1782429988790730752 |
---|---|
author | Pancar, Gunseli Sefika Eyupoglu, Oznur |
author_facet | Pancar, Gunseli Sefika Eyupoglu, Oznur |
author_sort | Pancar, Gunseli Sefika |
collection | PubMed |
description | BACKGROUND: Pityriasis rosea (PR) is an inflammatory skin disorder of unknown etiology. However, it is suggested to be related with the reactivation of human herpes virus 7 (HHV-7) and/or HHV-6. It is sometimes diffucult to distinguish PR from PR-like drug eruptions and other inflammatory disorders, so we need new parameters which are cheap and easy in determining PR. Red blood cell distribution width (RDW) and mean platelet volume (MPV) have been studied as inflammatory markers in recent studies. However, the RDW and MPV in PR patients have not been investigated. This is the first study investigating RDW and MPV parameters in PR. METHODS: This was a retrospective study of 127 patients and 127 healthy controls. MPV, RDW and the other laboratory tests were recorded. RESULTS: RDW levels of patients with PR were significantly lower than those of the controls (13.66 ± 2.68 and 14.00 ± 1.39, P < 0.01). The other inflammatory markers such as MPV (9.97 ± 0.99 and 10.0 ± 1.06, P = 0.7) and platelet (2.66.29 ± 62.85 and 277.41 ± 63.50, P = 0.3) were studied and statistically significant differences were not obtained. There were no significant differences found between the patient group and healthy controls in terms of hemoglobin, hematocrite, C-reactive protein (CRP), sedimentation, mean corpuscular volume (MCV), aspartate aminotransferase (AST), red blood cell (RBC), alanine aminotransferase (ALT), blood urea nitrogen (BUN), and creatinine parameters (P > 0.05). CONCLUSION: RDW can be used as a marker in diagnosing PR. |
format | Online Article Text |
id | pubmed-4852777 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Elmer Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-48527772016-05-25 Red Cell Distribution Width and Mean Platelet Volume in Patients With Pityriasis Rosea Pancar, Gunseli Sefika Eyupoglu, Oznur J Clin Med Res Original Article BACKGROUND: Pityriasis rosea (PR) is an inflammatory skin disorder of unknown etiology. However, it is suggested to be related with the reactivation of human herpes virus 7 (HHV-7) and/or HHV-6. It is sometimes diffucult to distinguish PR from PR-like drug eruptions and other inflammatory disorders, so we need new parameters which are cheap and easy in determining PR. Red blood cell distribution width (RDW) and mean platelet volume (MPV) have been studied as inflammatory markers in recent studies. However, the RDW and MPV in PR patients have not been investigated. This is the first study investigating RDW and MPV parameters in PR. METHODS: This was a retrospective study of 127 patients and 127 healthy controls. MPV, RDW and the other laboratory tests were recorded. RESULTS: RDW levels of patients with PR were significantly lower than those of the controls (13.66 ± 2.68 and 14.00 ± 1.39, P < 0.01). The other inflammatory markers such as MPV (9.97 ± 0.99 and 10.0 ± 1.06, P = 0.7) and platelet (2.66.29 ± 62.85 and 277.41 ± 63.50, P = 0.3) were studied and statistically significant differences were not obtained. There were no significant differences found between the patient group and healthy controls in terms of hemoglobin, hematocrite, C-reactive protein (CRP), sedimentation, mean corpuscular volume (MCV), aspartate aminotransferase (AST), red blood cell (RBC), alanine aminotransferase (ALT), blood urea nitrogen (BUN), and creatinine parameters (P > 0.05). CONCLUSION: RDW can be used as a marker in diagnosing PR. Elmer Press 2016-06 2016-05-25 /pmc/articles/PMC4852777/ /pubmed/27222672 http://dx.doi.org/10.14740/jocmr2535w Text en Copyright 2016, Pancar et al. http://creativecommons.org/licenses/by-nc/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Pancar, Gunseli Sefika Eyupoglu, Oznur Red Cell Distribution Width and Mean Platelet Volume in Patients With Pityriasis Rosea |
title | Red Cell Distribution Width and Mean Platelet Volume in Patients With Pityriasis Rosea |
title_full | Red Cell Distribution Width and Mean Platelet Volume in Patients With Pityriasis Rosea |
title_fullStr | Red Cell Distribution Width and Mean Platelet Volume in Patients With Pityriasis Rosea |
title_full_unstemmed | Red Cell Distribution Width and Mean Platelet Volume in Patients With Pityriasis Rosea |
title_short | Red Cell Distribution Width and Mean Platelet Volume in Patients With Pityriasis Rosea |
title_sort | red cell distribution width and mean platelet volume in patients with pityriasis rosea |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852777/ https://www.ncbi.nlm.nih.gov/pubmed/27222672 http://dx.doi.org/10.14740/jocmr2535w |
work_keys_str_mv | AT pancargunselisefika redcelldistributionwidthandmeanplateletvolumeinpatientswithpityriasisrosea AT eyupogluoznur redcelldistributionwidthandmeanplateletvolumeinpatientswithpityriasisrosea |