Red Cell Distribution Width and Mean Platelet Volume in Patients With Pityriasis Rosea

BACKGROUND: Pityriasis rosea (PR) is an inflammatory skin disorder of unknown etiology. However, it is suggested to be related with the reactivation of human herpes virus 7 (HHV-7) and/or HHV-6. It is sometimes diffucult to distinguish PR from PR-like drug eruptions and other inflammatory disorders,...

Descripción completa

Detalles Bibliográficos
Autores principales: Pancar, Gunseli Sefika, Eyupoglu, Oznur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elmer Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852777/
https://www.ncbi.nlm.nih.gov/pubmed/27222672
http://dx.doi.org/10.14740/jocmr2535w
_version_ 1782429988790730752
author Pancar, Gunseli Sefika
Eyupoglu, Oznur
author_facet Pancar, Gunseli Sefika
Eyupoglu, Oznur
author_sort Pancar, Gunseli Sefika
collection PubMed
description BACKGROUND: Pityriasis rosea (PR) is an inflammatory skin disorder of unknown etiology. However, it is suggested to be related with the reactivation of human herpes virus 7 (HHV-7) and/or HHV-6. It is sometimes diffucult to distinguish PR from PR-like drug eruptions and other inflammatory disorders, so we need new parameters which are cheap and easy in determining PR. Red blood cell distribution width (RDW) and mean platelet volume (MPV) have been studied as inflammatory markers in recent studies. However, the RDW and MPV in PR patients have not been investigated. This is the first study investigating RDW and MPV parameters in PR. METHODS: This was a retrospective study of 127 patients and 127 healthy controls. MPV, RDW and the other laboratory tests were recorded. RESULTS: RDW levels of patients with PR were significantly lower than those of the controls (13.66 ± 2.68 and 14.00 ± 1.39, P < 0.01). The other inflammatory markers such as MPV (9.97 ± 0.99 and 10.0 ± 1.06, P = 0.7) and platelet (2.66.29 ± 62.85 and 277.41 ± 63.50, P = 0.3) were studied and statistically significant differences were not obtained. There were no significant differences found between the patient group and healthy controls in terms of hemoglobin, hematocrite, C-reactive protein (CRP), sedimentation, mean corpuscular volume (MCV), aspartate aminotransferase (AST), red blood cell (RBC), alanine aminotransferase (ALT), blood urea nitrogen (BUN), and creatinine parameters (P > 0.05). CONCLUSION: RDW can be used as a marker in diagnosing PR.
format Online
Article
Text
id pubmed-4852777
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Elmer Press
record_format MEDLINE/PubMed
spelling pubmed-48527772016-05-25 Red Cell Distribution Width and Mean Platelet Volume in Patients With Pityriasis Rosea Pancar, Gunseli Sefika Eyupoglu, Oznur J Clin Med Res Original Article BACKGROUND: Pityriasis rosea (PR) is an inflammatory skin disorder of unknown etiology. However, it is suggested to be related with the reactivation of human herpes virus 7 (HHV-7) and/or HHV-6. It is sometimes diffucult to distinguish PR from PR-like drug eruptions and other inflammatory disorders, so we need new parameters which are cheap and easy in determining PR. Red blood cell distribution width (RDW) and mean platelet volume (MPV) have been studied as inflammatory markers in recent studies. However, the RDW and MPV in PR patients have not been investigated. This is the first study investigating RDW and MPV parameters in PR. METHODS: This was a retrospective study of 127 patients and 127 healthy controls. MPV, RDW and the other laboratory tests were recorded. RESULTS: RDW levels of patients with PR were significantly lower than those of the controls (13.66 ± 2.68 and 14.00 ± 1.39, P < 0.01). The other inflammatory markers such as MPV (9.97 ± 0.99 and 10.0 ± 1.06, P = 0.7) and platelet (2.66.29 ± 62.85 and 277.41 ± 63.50, P = 0.3) were studied and statistically significant differences were not obtained. There were no significant differences found between the patient group and healthy controls in terms of hemoglobin, hematocrite, C-reactive protein (CRP), sedimentation, mean corpuscular volume (MCV), aspartate aminotransferase (AST), red blood cell (RBC), alanine aminotransferase (ALT), blood urea nitrogen (BUN), and creatinine parameters (P > 0.05). CONCLUSION: RDW can be used as a marker in diagnosing PR. Elmer Press 2016-06 2016-05-25 /pmc/articles/PMC4852777/ /pubmed/27222672 http://dx.doi.org/10.14740/jocmr2535w Text en Copyright 2016, Pancar et al. http://creativecommons.org/licenses/by-nc/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Pancar, Gunseli Sefika
Eyupoglu, Oznur
Red Cell Distribution Width and Mean Platelet Volume in Patients With Pityriasis Rosea
title Red Cell Distribution Width and Mean Platelet Volume in Patients With Pityriasis Rosea
title_full Red Cell Distribution Width and Mean Platelet Volume in Patients With Pityriasis Rosea
title_fullStr Red Cell Distribution Width and Mean Platelet Volume in Patients With Pityriasis Rosea
title_full_unstemmed Red Cell Distribution Width and Mean Platelet Volume in Patients With Pityriasis Rosea
title_short Red Cell Distribution Width and Mean Platelet Volume in Patients With Pityriasis Rosea
title_sort red cell distribution width and mean platelet volume in patients with pityriasis rosea
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852777/
https://www.ncbi.nlm.nih.gov/pubmed/27222672
http://dx.doi.org/10.14740/jocmr2535w
work_keys_str_mv AT pancargunselisefika redcelldistributionwidthandmeanplateletvolumeinpatientswithpityriasisrosea
AT eyupogluoznur redcelldistributionwidthandmeanplateletvolumeinpatientswithpityriasisrosea