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Phase I Study of Oral Vinorelbine in Combination with Erlotinib in Advanced Non-Small Cell Lung Cancer (NSCLC) Using Two Different Schedules

PURPOSE: This study aimed to evaluate the safety, tolerability and pharmacokinetics of the combination of oral vinorelbine with erlotinib using the conventional (CSV) and metronomic (MSV) dosing schedules in patients with advanced non-small cell lung cancer (NSCLC). METHODS: This was an open-label,...

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Detalles Bibliográficos
Autores principales: Sutiman, Natalia, Zhang, Zhenxian, Tan, Eng Huat, Ang, Mei Kim, Tan, Shao-Weng Daniel, Toh, Chee Keong, Ng, Quan Sing, Chowbay, Balram, Lim, Wan-Teck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852941/
https://www.ncbi.nlm.nih.gov/pubmed/27135612
http://dx.doi.org/10.1371/journal.pone.0154316