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Phase I Study of Oral Vinorelbine in Combination with Erlotinib in Advanced Non-Small Cell Lung Cancer (NSCLC) Using Two Different Schedules
PURPOSE: This study aimed to evaluate the safety, tolerability and pharmacokinetics of the combination of oral vinorelbine with erlotinib using the conventional (CSV) and metronomic (MSV) dosing schedules in patients with advanced non-small cell lung cancer (NSCLC). METHODS: This was an open-label,...
Autores principales: | Sutiman, Natalia, Zhang, Zhenxian, Tan, Eng Huat, Ang, Mei Kim, Tan, Shao-Weng Daniel, Toh, Chee Keong, Ng, Quan Sing, Chowbay, Balram, Lim, Wan-Teck |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852941/ https://www.ncbi.nlm.nih.gov/pubmed/27135612 http://dx.doi.org/10.1371/journal.pone.0154316 |
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