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Evidence of a pathogenic role for CD8(+) T cells in anti-GABA(B) receptor limbic encephalitis

OBJECTIVES: To characterize the cellular autoimmune response in patients with γ-aminobutyric acid (GABA)(B) receptor antibody–associated limbic encephalitis (GABA(B)-R LE). METHODS: Patients underwent MRI, extensive neuropsychological assessment, and multiparameter flow cytometry of peripheral blood...

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Detalles Bibliográficos
Autores principales: Golombeck, Kristin S., Bönte, Kathrin, Mönig, Constanze, van Loo, Karen M., Hartwig, Marvin, Schwindt, Wolfram, Widman, Guido, Lindenau, Matthias, Becker, Albert J., Glatzel, Markus, Elger, Christian E., Wiendl, Heinz, Meuth, Sven G., Lohmann, Hubertus, Gross, Catharina C., Melzer, Nico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853055/
https://www.ncbi.nlm.nih.gov/pubmed/27213174
http://dx.doi.org/10.1212/NXI.0000000000000232