Dose-Dependent Effects of Glucocorticoids on Pulmonary Vascular Development in a Murine Model of Hyperoxic Lung Injury

BACKGROUND: Exposure of neonatal mice to hyperoxia results in pulmonary vascular remodeling and aberrant phosphodiesterase-5 (PDE5) signaling. Although glucocorticoids are frequently utilized in the NICU, little is known about their effects on the developing pulmonary vasculature and on PDE5. We sou...

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Detalles Bibliográficos
Autores principales: Perez, Marta, Wisniewska, Kamila, Lee, Keng Jin, Cardona, Herminio J., Taylor, Joann M., Farrow, Kathryn N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853243/
https://www.ncbi.nlm.nih.gov/pubmed/26756781
http://dx.doi.org/10.1038/pr.2016.1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853243/
https://www.ncbi.nlm.nih.gov/pubmed/26756781
http://dx.doi.org/10.1038/pr.2016.1

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