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Loss of ATF3 Promotes Hormone-induced Prostate Carcinogenesis and the Emergence of CK5(+)CK8(+) Epithelial Cells

Steroid sex hormones can induce prostate carcinogenesis, and are thought to contribute to the development of prostate cancer during aging. However, the mechanism for hormone-induced prostate carcinogenesis remains elusive. Here we report that activating transcription factor 3 (ATF3) – a broad stress...

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Detalles Bibliográficos
Autores principales: Wang, Ziyan, Kim, Jaejik, Teng, Yong, Ding, Han-Fei, Zhang, Junran, Hai, Tsonwin, Cowell, John K., Yan, Chunhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853303/
https://www.ncbi.nlm.nih.gov/pubmed/26522727
http://dx.doi.org/10.1038/onc.2015.417