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Non-catalytic roles for TET1 protein negatively regulating neuronal differentiation through srGAP3 in neuroblastoma cells

The methylcytosine dioxygenases TET proteins (TET1, TET2, and TET3) play important regulatory roles in neural function. In this study, we investigated the role of TET proteins in neuronal differentiation using Neuro2a cells as a model. We observed that knockdown of TET1, TET2 or TET3 promoted neuron...

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Detalles Bibliográficos
Autores principales: Gao, Jie, Ma, Yue, Fu, Hua-Lin, Luo, Qian, Wang, Zhen, Xiao, Yu-Huan, Yang, Hao, Cui, Da-Xiang, Jin, Wei-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853314/
https://www.ncbi.nlm.nih.gov/pubmed/27113584
http://dx.doi.org/10.1007/s13238-016-0267-4