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Yap1 plays a protective role in suppressing free fatty acid-induced apoptosis and promoting beta-cell survival
Mammalian pancreatic β-cells play a pivotal role in development and glucose homeostasis through the production and secretion of insulin. Functional failure or decrease in β-cell number leads to type 2 diabetes (T2D). Despite the physiological importance of β-cells, the viability of β-cells is often...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Higher Education Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853318/ https://www.ncbi.nlm.nih.gov/pubmed/27000077 http://dx.doi.org/10.1007/s13238-016-0258-5 |