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An inhibitor of chondroitin sulfate proteoglycan synthesis promotes central nervous system remyelination

Remyelination is the generation of new myelin sheaths after injury facilitated by processes of differentiating oligodendrocyte precursor cells (OPCs). Although this repair phenomenon occurs in lesions of multiple sclerosis patients, many lesions fail to completely remyelinate. A number of factors ha...

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Detalles Bibliográficos
Autores principales: Keough, Michael B., Rogers, James A., Zhang, Ping, Jensen, Samuel K., Stephenson, Erin L., Chen, Tieyu, Hurlbert, Mitchel G., Lau, Lorraine W., Rawji, Khalil S., Plemel, Jason R., Koch, Marcus, Ling, Chang-Chun, Yong, V. Wee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853428/
https://www.ncbi.nlm.nih.gov/pubmed/27115988
http://dx.doi.org/10.1038/ncomms11312