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Effect of IL-4 on the Development and Function of Memory-like CD8 T Cells in the Peripheral Lymphoid Tissues

Unlike conventional T cells, innate CD8 T cells develop a memory-like phenotype in the thymus and immediately respond upon antigen stimulation, similar to memory T cells. The development of innate CD8 T cells in the thymus is known to require IL-4, which upregulates Eomesodermin (Eomes). These featu...

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Detalles Bibliográficos
Autores principales: Park, Hi-Jung, Lee, Ara, Lee, Jae-Il, Park, Seong Hoe, Ha, Sang-Jun, Jung, Kyeong Cheon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Immunologists 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853498/
https://www.ncbi.nlm.nih.gov/pubmed/27162529
http://dx.doi.org/10.4110/in.2016.16.2.126