Decreased miR-199 augments visceral pain in patients with IBS through translational upregulation of TRPV1

OBJECTIVE: Many patients with irritable bowel syndrome IBS not only have abdominal pain but also may suffer from visceral hypersensitivity and heighted visceral nociception. Moreover, IBS has few effective therapeutic agents and mechanisms of disease are unclear. Our goals were to (i) identify micro...

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Detalles Bibliográficos
Autores principales: Zhou, QiQi, Yang, Liuqing, Larson, Scott, Basra, Sapreet, Merwat, Shehzad, Tan, Alai, Croce, Carlo, Verne, G Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Neurogastroenterology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853572/
https://www.ncbi.nlm.nih.gov/pubmed/25681400
http://dx.doi.org/10.1136/gutjnl-2013-306464

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853572/
https://www.ncbi.nlm.nih.gov/pubmed/25681400
http://dx.doi.org/10.1136/gutjnl-2013-306464

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