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Decreased miR-199 augments visceral pain in patients with IBS through translational upregulation of TRPV1
OBJECTIVE: Many patients with irritable bowel syndrome IBS not only have abdominal pain but also may suffer from visceral hypersensitivity and heighted visceral nociception. Moreover, IBS has few effective therapeutic agents and mechanisms of disease are unclear. Our goals were to (i) identify micro...
Autores principales: | Zhou, QiQi, Yang, Liuqing, Larson, Scott, Basra, Sapreet, Merwat, Shehzad, Tan, Alai, Croce, Carlo, Verne, G Nicholas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853572/ https://www.ncbi.nlm.nih.gov/pubmed/25681400 http://dx.doi.org/10.1136/gutjnl-2013-306464 |
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