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Synovial CD4+ T-cell-derived GM-CSF supports the differentiation of an inflammatory dendritic cell population in rheumatoid arthritis

OBJECTIVE: A population of synovial inflammatory dendritic cells (infDCs) has recently been identified in rheumatoid arthritis (RA) and is thought to be monocyte-derived. Here, we investigated the role and source of granulocyte macrophage-colony-stimulating factor (GM-CSF) in the differentiation of...

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Detalles Bibliográficos
Autores principales: Reynolds, G, Gibbon, J R, Pratt, A G, Wood, M J, Coady, D, Raftery, G, Lorenzi, A R, Gray, A, Filer, A, Buckley, C D, Haniffa, M A, Isaacs, J D, Hilkens, C M U
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853576/
https://www.ncbi.nlm.nih.gov/pubmed/25923217
http://dx.doi.org/10.1136/annrheumdis-2014-206578