Inhibiting DNA methylation switches adipogenesis to osteoblastogenesis by activating Wnt10a

Both adipocytes and osteoblasts share the mesodermal lineage that derives from mesenchymal stem cells. Most studies investigating the mechanisms underlying the regulation of adipogenic or osteoblastogenic development focus on transcriptional pathways; little is known about the epigenetic mechanisms...

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Detalles Bibliográficos
Autores principales: Chen, Yii-Shyuan, Wu, Rui, Yang, Xiaosong, Kou, Shuping, MacDougald, Ormond A., Yu, Liqing, Shi, Hang, Xue, Bingzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853709/
https://www.ncbi.nlm.nih.gov/pubmed/27136753
http://dx.doi.org/10.1038/srep25283

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853709/
https://www.ncbi.nlm.nih.gov/pubmed/27136753
http://dx.doi.org/10.1038/srep25283

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