Epigenetically regulated miR-449a enhances hepatitis B virus replication by targeting cAMP-responsive element binding protein 5 and modulating hepatocytes phenotype

Cellular microRNAs (miRNAs) are able to influence hepatitis B virus (HBV) replication directly by binding to HBV transcripts or indirectly by targeting cellular factors. Here, we investigate the effect of epigenetically regulated miR-449a on HBV replication and the underlying mechanisms. miR-449a ex...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoyong, Liu, Hongyan, Xie, Zhanglian, Deng, Wangyu, Wu, Chunchen, Qin, Bo, Hou, Jinlin, Lu, Mengji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853741/
https://www.ncbi.nlm.nih.gov/pubmed/27138288
http://dx.doi.org/10.1038/srep25389

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853741/
https://www.ncbi.nlm.nih.gov/pubmed/27138288
http://dx.doi.org/10.1038/srep25389

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