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Up-regulation of Interferon-inducible protein 16 contributes to psoriasis by modulating chemokine production in keratinocytes

Psoriasis is a common chronic inflammatory skin disease characterized by epidermal hyperplasia and dermal inflammation. Keratinocyte activation is known to play a critical role in psoriasis, but the underlying mechanism remains unclear. Interferon-inducible protein 16 (IFI16), an innate immune syste...

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Detalles Bibliográficos
Autores principales: Cao, Tianyu, Shao, Shuai, Li, Bing, Jin, Liang, Lei, Jie, Qiao, Hongjiang, Wang, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853747/
https://www.ncbi.nlm.nih.gov/pubmed/27137868
http://dx.doi.org/10.1038/srep25381