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Combined sodium ion sensitivity in agonist binding and internalization of vasopressin V1b receptors
Reducing Na(+) in the extracellular environment may lead to two beneficial effects for increasing agonist binding to cell surface G-protein coupled receptors (GPCRs): reduction of Na(+)-mediated binding block and reduce of receptor internalization. However, such combined effects have not been explor...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853784/ https://www.ncbi.nlm.nih.gov/pubmed/27138239 http://dx.doi.org/10.1038/srep25327 |