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Resveratrol Inhibition of Rac1-Derived Reactive Oxygen Species by AMPK Decreases Blood Pressure in a Fructose-Induced Rat Model of Hypertension

Recent studies have reported that the activation of AMP-activated protein kinase (AMPK) suppressed oxidative stress. The aim of this study was to examine whether the activation of AMPK in the brain decreased Rac1-induced ROS generation, thereby reducing blood pressure (BP) in rats with fructose-indu...

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Detalles Bibliográficos
Autores principales: Cheng, Pei-Wen, Lee, Hui-Chieh, Lu, Pei-Jung, Chen, Hsin-Hung, Lai, Chi-Cheng, Sun, Gwo-Ching, Yeh, Tung-Chen, Hsiao, Michael, Lin, Yu-Te, Liu, Chun-Peng, Tseng, Ching-Jiunn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853785/
https://www.ncbi.nlm.nih.gov/pubmed/27138844
http://dx.doi.org/10.1038/srep25342