Cargando…

Cloning and Variation of Ground State Intestinal Stem Cells

Stem cells of the gastrointestinal tract, pancreas, liver, and other columnar epithelia collectively resist cloning in their elemental states. Here we demonstrate the cloning and propagation of highly clonogenic, “ground state” stem cells of the human intestine and colon. We show that derived stem c...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Xia, Yamamoto, Yusuke, Wilson, Lane H., Zhang, Ting, Howitt, Brooke, Farrow, Melissa A., Kern, Florian, Ning, Gang, Hong, Yue, Khor, Chiea Chuen, Chevalier, Benoit, Bertrand, Denis, Wu, Lingyan, Nagarajan, Niranjan, Sylvester, Francisco A., Hyams, Jeffrey S., Devers, Thomas, Bronson, Roderick, Lacy, D. Borden, Ho, Khek Yu, Crum, Christopher P., McKeon, Frank, Xian, Wa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853906/
https://www.ncbi.nlm.nih.gov/pubmed/26040716
http://dx.doi.org/10.1038/nature14484