Engaging Alkenyl Halides with Alkylsilicates via Photoredox Dual Catalysis

[Image: see text] Single-electron transmetalation via photoredox/nickel dual catalysis provides the opportunity for the construction of C(sp(3))–C(sp(2)) bonds through the transfer of alkyl radicals under very mild reaction conditions. A general procedure for the cross-coupling of primary and second...

Descripción completa

Detalles Bibliográficos
Autores principales: Patel, Niki R., Kelly, Christopher B., Jouffroy, Matthieu, Molander, Gary A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854195/
https://www.ncbi.nlm.nih.gov/pubmed/26828317
http://dx.doi.org/10.1021/acs.orglett.6b00024
_version_ 1782430189640220672
author Patel, Niki R.
Kelly, Christopher B.
Jouffroy, Matthieu
Molander, Gary A.
author_facet Patel, Niki R.
Kelly, Christopher B.
Jouffroy, Matthieu
Molander, Gary A.
author_sort Patel, Niki R.
collection PubMed
description [Image: see text] Single-electron transmetalation via photoredox/nickel dual catalysis provides the opportunity for the construction of C(sp(3))–C(sp(2)) bonds through the transfer of alkyl radicals under very mild reaction conditions. A general procedure for the cross-coupling of primary and secondary (bis-catecholato)alkylsilicates with alkenyl halides is presented. The developed method allows not only alkenyl bromides and iodides but also previously underexplored alkenyl chlorides to be employed.
format Online
Article
Text
id pubmed-4854195
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher American Chemical Society
record_format MEDLINE/PubMed
spelling pubmed-48541952017-02-01 Engaging Alkenyl Halides with Alkylsilicates via Photoredox Dual Catalysis Patel, Niki R. Kelly, Christopher B. Jouffroy, Matthieu Molander, Gary A. Org Lett [Image: see text] Single-electron transmetalation via photoredox/nickel dual catalysis provides the opportunity for the construction of C(sp(3))–C(sp(2)) bonds through the transfer of alkyl radicals under very mild reaction conditions. A general procedure for the cross-coupling of primary and secondary (bis-catecholato)alkylsilicates with alkenyl halides is presented. The developed method allows not only alkenyl bromides and iodides but also previously underexplored alkenyl chlorides to be employed. American Chemical Society 2016-02-01 2016-02-19 /pmc/articles/PMC4854195/ /pubmed/26828317 http://dx.doi.org/10.1021/acs.orglett.6b00024 Text en Copyright © 2016 American Chemical Society This is an open access article published under an ACS AuthorChoice License (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html) , which permits copying and redistribution of the article or any adaptations for non-commercial purposes.
spellingShingle Patel, Niki R.
Kelly, Christopher B.
Jouffroy, Matthieu
Molander, Gary A.
Engaging Alkenyl Halides with Alkylsilicates via Photoredox Dual Catalysis
title Engaging Alkenyl Halides with Alkylsilicates via Photoredox Dual Catalysis
title_full Engaging Alkenyl Halides with Alkylsilicates via Photoredox Dual Catalysis
title_fullStr Engaging Alkenyl Halides with Alkylsilicates via Photoredox Dual Catalysis
title_full_unstemmed Engaging Alkenyl Halides with Alkylsilicates via Photoredox Dual Catalysis
title_short Engaging Alkenyl Halides with Alkylsilicates via Photoredox Dual Catalysis
title_sort engaging alkenyl halides with alkylsilicates via photoredox dual catalysis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854195/
https://www.ncbi.nlm.nih.gov/pubmed/26828317
http://dx.doi.org/10.1021/acs.orglett.6b00024
work_keys_str_mv AT patelnikir engagingalkenylhalideswithalkylsilicatesviaphotoredoxdualcatalysis
AT kellychristopherb engagingalkenylhalideswithalkylsilicatesviaphotoredoxdualcatalysis
AT jouffroymatthieu engagingalkenylhalideswithalkylsilicatesviaphotoredoxdualcatalysis
AT molandergarya engagingalkenylhalideswithalkylsilicatesviaphotoredoxdualcatalysis

Ejemplares similares