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Up-Regulation of CREG Expression by the Transcription Factor GATA1 Inhibits High Glucose- and High Palmitate-Induced Apoptosis in Human Umbilical Vein Endothelial Cells

BACKGROUND: Endothelial cell (EC) apoptosis plays a vital role in the pathogenesis of atherosclerosis in patients with diabetes mellitus (DM), but the underlying mechanism remains unclear. Cellular repressor of E1A-stimulated genes (CREG) is a novel gene reported to be involved in maintaining the ho...

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Detalles Bibliográficos
Autores principales: Liu, Yanxia, Tian, Xiaoxiang, Li, Yang, Liu, Dan, Liu, Meili, Zhang, Xiaolin, Zhang, Quanyu, Yan, Chenghui, Han, Yaling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854376/
https://www.ncbi.nlm.nih.gov/pubmed/27139506
http://dx.doi.org/10.1371/journal.pone.0154861